This article details the five candidates who raised the most money and lost their election. In the 2022 election cycle, 79 of 120 general elections were contested. The losing candidates are shown along with the percentage of the vote they received compared to the winner. In cases where the race was pushed to a runoff, vote percentages for both advancing candidates are included.

This article details the five most expensive contested general elections in the House of Representatives.

While campaign finance is not the only factor in electoral outcomes, successful fundraising can provide a candidate with advantages during a campaign. Fundraising can also indicate party momentum.